MCAS Article

Source: 
https://mastcellsunited.com

Link: 
https://mastcellsunited.com/2018/10/10/mcas-and-cannabidiol-cbd/

Article Summary:
The article explores the roles and potential benefits of endocannabinoids and phytocannabinoids, particularly cannabidiol (CBD), in human health. Endocannabinoids are naturally occurring substances in the body that influence various physiological functions such as relaxation, sleep, hunger, and immune response. They are crucial for maintaining body homeostasis.  Phytocannabinoids, derived from plants like hemp, are similar to endocannabinoids and include CBD, known for its non-psychoactive properties. Despite being distinct from THC, CBD has faced stigma due to its association with marijuana. However, research suggests CBD has therapeutic potential without the addictive properties of THC.  Studies highlight CBD’s effectiveness in treating conditions such as epilepsy, anxiety, depression, cardiovascular disease, and inflammation. Research also points to its role in reducing drug-seeking behavior and potentially alleviating symptoms of mast cell activation syndrome (MCAS) and allergic diseases.  The article acknowledges limited research within the U.S. medical community due to stigma and regulatory barriers but notes promising international studies. While CBD appears beneficial for many, potential side effects like GI issues and fatigue should be considered, especially for patients with MCAS who may be more sensitive. CBD’s interaction with other medications underscores the importance of medical consultation before use.  Overall, the article emphasizes CBD’s emerging role in therapeutic medicine, particularly for conditions involving inflammation and neurological disorders, while highlighting the need for further research and cautious use in clinical settings.