Pain and Inflammation Article

Article Summary:
CBD, known for its non-intoxicating properties unlike THC, has emerged as a focal point for potential health benefits. Operating via the endocannabinoid system, CBD interacts with receptors influencing diverse bodily functions, particularly pain perception and inflammation. While ongoing studies continue to delve into CBD’s effectiveness as an analgesic, initial findings are promising, indicating its potential to alleviate pain across different medical conditions. In the United States, FDA approval for CBD-based medications is limited to Epidiolex, primarily prescribed for rare forms of epilepsy. Conversely, other countries have sanctioned CBD for managing conditions such as multiple sclerosis and cancer-related pain. Research underscores the efficacy of CBD, sometimes in tandem with THC, in managing chronic pain, encompassing neuropathic and nociceptive pain variants. Notably, trials on Sativex, a CBD-THC spray, have demonstrated significant reductions in pain associated with cancer and multiple sclerosis, prompting further investigations into broader applications within the U.S.